Tsuyoshi Takeda Selected Research

Vitamin K 2 (Vitamin K2)

1/2021	Retracted Note: Effects of Vitamin K2 on Osteoporosis.
1/2018	Retraction Note to: Efficacy of Menatetrenone (Vitamin K2) against Non-Vertebral and Hip Fractures in Patients with Neurological Diseases : Meta-Analysis of Three Randomized, Controlled Trials.
9/2012	Strategy for prevention of hip fractures in patients with Parkinson's disease.
5/2011	Effect of vitamin K2 on cortical and cancellous bone mass and hepatic lipids in rats with combined methionine-choline deficiency.
3/2011	Bone quality and vitamin K2 in type 2 diabetes: review of preclinical and clinical studies.
8/2009	Prevention of hip fractures by exposure to sunlight and pharmacotherapy in patients with Alzheimer's disease.
4/2009	High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women: a review of the literature.
1/2009	Efficacy of menatetrenone (vitamin K2) against non-vertebral and hip fractures in patients with neurological diseases: meta-analysis of three randomized, controlled trials.
12/2006	Menatetrenone (vitamin K2) and bone quality in the treatment of postmenopausal osteoporosis.
10/2006	Beneficial effect of pretreatment and treatment continuation with risedronate and vitamin K2 on cancellous bone loss after ovariectomy in rats: a bone histomorphometry study.

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Tsuyoshi Takeda Research Topics

Disease

37	Osteoporosis 08/2021 - 01/2002
25	Bone Resorption 08/2021 - 01/2002
18	Pancreatic Neoplasms (Pancreatic Cancer) 09/2022 - 01/2018
14	Metabolic Bone Diseases (Osteopenia) 01/2021 - 01/2002
10	Back Pain (Backache) 08/2021 - 01/2003
8	Neoplasms (Cancer) 09/2022 - 01/2002
8	Hip Fractures (Intertrochanteric Fractures) 01/2018 - 01/2006
6	Stroke (Strokes) 01/2021 - 01/2004
6	Parkinson Disease (Parkinson's Disease) 01/2021 - 01/2004
6	Postmenopausal Osteoporosis 01/2012 - 09/2003
6	Body Weight (Weight, Body) 01/2011 - 01/2002
4	Neoplasm Metastasis (Metastasis) 09/2022 - 01/2002
4	Biliary Tract Neoplasms (Biliary Tract Cancer) 07/2021 - 01/2016
4	Alzheimer Disease (Alzheimer's Disease) 01/2012 - 05/2008
4	Osteoporotic Fractures 01/2011 - 09/2003
4	Vitamin K Deficiency 01/2011 - 10/2003
4	Pain (Aches) 06/2009 - 01/2002
4	Osteogenesis Imperfecta (Lobstein Disease) 06/2005 - 01/2002
3	Duodenal Obstruction 05/2022 - 11/2020
3	Cholangitis 05/2022 - 11/2020
3	Pathologic Constriction (Stenosis) 01/2022 - 12/2020
3	Intervertebral Disc Displacement (Herniated Disc) 01/2011 - 08/2006
2	Sarcopenia 07/2021 - 04/2021
2	Rheumatoid Arthritis 05/2021 - 09/2013
2	Anorexia 04/2021 - 01/2021
2	Pancreatitis 01/2021 - 11/2020
2	Vitamin D Deficiency 01/2021 - 01/2004
2	Type 2 Diabetes Mellitus (MODY) 03/2011 - 01/2011
2	Knee Osteoarthritis 01/2011 - 03/2010
2	Hyperparathyroidism 01/2011 - 08/2009
2	Magnesium Deficiency (Deficiency, Magnesium) 12/2006 - 04/2006
1	Hyperplasia 05/2022
1	Mucinous Adenocarcinoma (Mucinous Carcinoma) 05/2022
1	Turcot syndrome 01/2022
1	Carcinogenesis 01/2022
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 12/2021
1	Enteritis 10/2021
1	Dihydropyrimidine Dehydrogenase Deficiency 10/2021
1	Adenocarcinoma 10/2021
1	Neutropenia 07/2021
1	Cachexia 07/2021
1	Hemobilia 07/2021
1	Disease Progression 07/2021

Drug/Important Bio-Agent (IBA)

32	Alendronate (Alendronate Sodium)FDA LinkGeneric 08/2021 - 01/2002
18	Vitamin K 2 (Vitamin K2)IBA 01/2021 - 01/2003
17	Risedronic Acid (Actonel)FDA LinkGeneric 05/2021 - 10/2003
14	Etidronic Acid (HEDP)FDA LinkGeneric 01/2012 - 01/2002
11	Diphosphonates (Bisphosphonates)IBA 01/2021 - 10/2003
11	Collagen Type I (Type I Collagen)IBA 01/2011 - 01/2002
10	Gemcitabine FDA Link 10/2021 - 01/2019
10	alfacalcidolIBA 01/2011 - 01/2002
9	menatetrenoneIBA 01/2021 - 09/2003
8	GlucocorticoidsIBA 05/2021 - 06/2005
8	CalciumIBA 01/2011 - 07/2004
7	130-nm albumin-bound paclitaxelIBA 08/2021 - 05/2020
7	Vitamin D FDA LinkGeneric 01/2021 - 01/2004
7	EnzymesIBA 12/2018 - 01/2002
7	OsteocalcinIBA 09/2012 - 01/2002
6	folfirinoxIBA 08/2021 - 05/2020
6	ImmunosorbentsIBA 12/2005 - 01/2002
5	Pharmaceutical PreparationsIBA 03/2021 - 01/2004
5	Raloxifene Hydrochloride (Evista)FDA Link 01/2012 - 01/2006
5	Alkaline PhosphataseIBA 01/2011 - 01/2002
5	Parathyroid Hormone (Parathormone)IBA 11/2007 - 01/2004
4	Calcitriol (Calcijex)FDA LinkGeneric 01/2019 - 06/2005
2	MetalsIBA 05/2022 - 11/2020
2	Leucovorin (Folinic Acid)FDA Link 01/2021 - 01/2019
2	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 05/2003
2	Anabolic AgentsIBA 01/2011 - 09/2003
2	MineralsIBA 08/2009 - 12/2006
2	elcatoninIBA 06/2009 - 01/2002
2	Ibandronic Acid (Boniva)FDA Link 11/2007 - 05/2006
2	StrontiumIBA 11/2007 - 05/2006
2	Glutamic Acid (Glutamate)FDA Link 10/2003 - 09/2003
1	Codon (Codons)IBA 09/2022
1	Formaldehyde (Formol)FDA Link 09/2022
1	ParaffinIBA 09/2022
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Monoclonal AntibodiesIBA 12/2021
1	obinutuzumabIBA 12/2021
1	Bendamustine Hydrochloride FDA Link 12/2021
1	dihydrouracilIBA 10/2021
1	UracilIBA 10/2021
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 08/2021
1	SodiumIBA 05/2021

Therapy/Procedure

15	Drug Therapy (Chemotherapy) 09/2022 - 08/2009
6	Stents 05/2022 - 11/2020
6	Therapeutics 08/2021 - 01/2008
4	Neoadjuvant Therapy 09/2022 - 11/2020
3	Self Expandable Metallic Stents 05/2022 - 11/2020
3	Conservative Treatment 01/2011 - 08/2006
2	Enteral Nutrition (Feeding, Tube) 01/2021 - 04/2020
2	Aftercare (After-Treatment) 11/2010 - 06/2003
2	Activities of Daily Living (ADL) 12/2003 - 01/2002
1	Pancreatectomy 09/2022
1	Adjuvant Chemotherapy 05/2022
1	Gastric Bypass (Roux-en-Y Gastric Bypass) 07/2021
1	Immunotherapy 07/2021
1	Catheters 06/2021